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Blue Brain Project Moves Onto Whole Brain, Really?

Originally posted on sciy.org by Ron Anastasia on Mon 03 Dec 2007 02:40 PM PST  


Brain Waves

November 28, 2007

Blue Brain Project Moves Onto Whole Brain, Really?

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Posted by Zack Lynch

bluebrain_x220.jpg

"An ambitious project to create an accurate computer model of the brain has reached an impressive milestone, writes today's Technology Review. "Scientists in Switzerland working with IBM researchers have shown that their computer simulation of the neocortical column, arguably the most complex part of a mammal's brain, appears (emphasis added) to behave like its biological counterpart. By demonstrating that their simulation is realistic, the researchers say, these results suggest that an entire mammal brain could be completely modeled within three years, and a human brain within the next decade.

"What we're doing is reverse-engineering the brain," says Henry Markram, codirector of the Brain Mind Institute at the Ecole Polytechnique Fédérale de Lausanne, in Switzerland, who led the work, called the Blue Brain project, which began in 2005. By mimicking the behavior of the brain down to the individual neuron, the researchers aim to create a modeling tool that can be used by neuroscientists to run experiments, test hypotheses, and analyze the effects of drugs more efficiently than they could using real brain tissue. The model of part of the brain was completed last year, says Markram. But now, after extensive testing comparing its behavior with results from biological experiments, he is satisfied that the simulation is accurate enough that the researchers can proceed with the rest of the brain."

The article goes onto to share the response of Christof Koch from Caltech who calls the 10 year target of modeling the human brain "ridiculous." Despite the fantastic progress to date I agree with Christof on this.

(Associated graphic is a representation of a mammalian neocortical column, the basic building block of the cortex. The representation shows the complexity of this part of the brain, which has now been modeled using a supercomputer. Credit: BBP/EPFL) Looks kind of like a Jackson Pollock painting.

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